Pancreatic insulinomas (IP), are uncommon tumors that come from the beta cells of pancreatic islets, which are characterized by producing insulin excessively, therefore causing hypoglycemia; which is manifested by neuroglycopenic and autonomic symptoms. IP diagnosis is proposed by Whipple's triad, characterized by hypoglycemia, neuroglycopenic symptoms and the reversal of the symptoms following the administration of glucose. Surgery remains the treatment of choice for IP, either by laparotomy or laparoscopy, performing enucleation or segmental pancreatectomies. These procedures are not free of complications, most notably are pancreatic fistula, and pseudocyst formation, and the development of diabetes mellitus. The aim of this paper is to report the personal experience in treating consecutive patients with PI and discuss the related literature.