| dc.creator | Roa E,Iván | |
| dc.creator | Ibacache S,Gilda | |
| dc.creator | Carvallo B,Julio | |
| dc.creator | Melo S,Angélica | |
| dc.creator | Araya O,Juan | |
| dc.creator | De Aretxabala U,Xabier | |
| dc.creator | Figueroa P,Miguel | |
| dc.creator | Barrientos C,Fernando | |
| dc.creator | Figueroa Z,Carlos | |
| dc.date | 1999-09-01 | |
| dc.date.accessioned | 2022-08-29T19:33:25Z | |
| dc.date.available | 2022-08-29T19:33:25Z | |
| dc.identifier | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871999000900003 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/205734 | |
| dc.description | Background: Gallbladder cancer is frequent in Chile and there is sparse information about the association between this type of cancer and the presence of bacteria in the gallbladder bile. Aim: To determine the presence of aerobic bacteria in gallbladder bile in patients with and without gallbladder cancer. Material and methods: A microbiological analysis of bile and pathological study was performed in 608 gallbladders, obtained during to cholecystectomies performed to 513 women and 95 men aged 44 years old as a mean. Results: Pathological study showed a chronic cholecystitis in 468 cases (77%), an acute cholecystitis in 140 (33%), cancer in 24 (3.9%) and dysplasia in 5 cases (0.8%). A positive culture was obtained in 22.5% of women and 28.5% of males. Twenty seven percent of women over 30 years old had positive cultures compared with 10% of younger women (p <0.001). Thirty two percent of acute cholecystitis had positive cultures, compared with 24% of chronic cholecystitis (p=0.03). E Coli was isolated in 51% of positive cases, Streptococci-Enterococci in 24%, Enterobacter sp in 9%, Klebsiella and Proteus in lower proportions. Salmonella sp was isolated in 4 cases, being all women with chronic cholecystitis. Thirteen of 29 cases with cancer or dysplasia had positive cultures (45%), compared with 25% of patients with inflammatory gallbladder diseases (p=0.02). Streptococci-Enterococci were isolated in 7 cases and Enterobacter sp in three. Conclusions: The presence of Salmonella sp in gallbladder bile was not frequent in the studied patients. Its role in the pathogenesis of gallbladder cancer must be reassessed. | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.relation | 10.4067/S0034-98871999000900003 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista médica de Chile v.127 n.9 1999 | |
| dc.subject | Bacterial infectious | |
| dc.subject | Bile | |
| dc.subject | Biliary tract surgery | |
| dc.subject | Gallbladder neoplasms | |
| dc.title | Estudio bacteriológico de la bilis vesicular en un área de alto riesgo de cáncer vesicular | |
