| dc.creator | Arbildo, Heber | |
| dc.creator | Gamarra, Luis | |
| dc.creator | Rojas, Sandra | |
| dc.creator | Infantes, Edward | |
| dc.creator | Lamas, Cesar | |
| dc.creator | Vásquez, Hernán | |
| dc.date | 2017-05-24 | |
| dc.identifier | http://www.joralres.com/index.php/JOR/article/view/joralres.2017.036 | |
| dc.identifier | 10.17126/joralres.2017.036 | |
| dc.description | Background: There is currently no gold standard biomaterial for the treatment of periodontal intrabony defects (PIDs). One of the current options is the use of platelet-rich fibrin (PRF). Objective: To determine the clinical effect of PRF in the treatment of PID through a systematic review and meta-analysis. Materials and Methods: A literature search was conducted up to February 2017 in the following biomedical databases: Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS and in the Cochrane Central Register of Clinical Trials. The selection criteria included: randomized clinical trials published in the last 5 years, reporting clinical effects (probing depth, clinical insertion level or gingival recession), with a follow-up time equal to or greater than 6 months, and sample size larger than or equal to 10 patients reporting the use of PRF as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference. Results: The search strategy yielded 20 articles. A reduction in probing depth and an increase in clinical insertion level or a reduction in gingival recession is reported, when using PRF alone or in combination with another biomaterial or substance that stimulates tissue regeneration. Conclusion: The literature suggests that the use of PRF in the treatment of PIDs has a beneficial clinical effect when compared to control treatments. | en-US |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Facultad de Odontología, Universidad de Concepción, Chile. | en-US |
| dc.relation | http://www.joralres.com/index.php/JOR/article/view/joralres.2017.036/311 | |
| dc.source | Journal of Oral Research; Vol 6 No 5; 127-135 | es-ES |
| dc.source | Journal of Oral Research; Vol 6 No 5; 127-135 | en-US |
| dc.source | 0719-2479 | |
| dc.source | 0719-2460 | |
| dc.subject | Platelet-rich fibrin; Periodontitis; Review; Meta-analysis. | en-US |
| dc.title | Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. Systematic review and meta-analysis. | en-US |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.type | Reviews | en-US |
