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dc.contributoren-US
dc.creatorTorres, Solange
dc.creatorCabrera Pardo, Jaime R.
dc.creatorAlonso, Felipe
dc.creatorBustos, Evelyn
dc.creatorPérez, Claudia
dc.creatorPalfner, Goetz
dc.creatorHernández, Víctor
dc.creatorUriarte, Eugenio
dc.creatorBecerra, José
dc.date2016-12-10
dc.date.accessioned2019-04-16T16:43:00Z
dc.date.available2019-04-16T16:43:00Z
dc.identifierhttps://www.jcchems.com/index.php/JCCHEMS/article/view/116
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/42460
dc.descriptionThe present study aims to investigate the effects of ultraviolet radiation (type B) on the steroid and fatty acids content, phenolic compounds and biological activities of Stereum hirsutum wild fruiting bodies, which has been used by both Chinese and Korean folk medicine to treat cancer and recently as functional food. From another perspective, the distribution of steroid derivatives as well as fatty acids underwent significant changes after UV exposure over time. In our model of study UV-B radiation induced a decrease in the relative abundance of ergosterol derivatives while squalene increased. We also detected that UVB radiation (1.2 W m-2) enhanced the antioxidant activity of Stereum hirsutum, with the acetonic extract after 48 hours of radiation the most efficient with a half-maximal inhibitory concentration (IC50) of 339.9 μg/mL. Gas-mass chromatography (GC-MS) analysis at this 48 hours stage revealed a high content of phenolic compounds (70%). We observed a decrease in the antibacterial activity against Escherichia coli, Salmonella typhi and Salmonella typhimurium compared to their respective controls. The study concludes that UV-B influences the pathway of secondary metabolites to induce changes metabolic in the composition of sterols and fatty acids and increasing the abundance of antioxidant compounds in S. hirsutum. en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedad Chilena de Químicaen-US
dc.relationhttps://www.jcchems.com/index.php/JCCHEMS/article/view/116/101
dc.rightsCopyright (c) 2017 Solange Torres, Jaime R. Cabrera Pardo, Felipe Alonso, Evelyn Bustos, Claudia Pérez, Goetz Palfner, Víctor Hernández, Eugenio Uriarte, José Becerraen-US
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceJournal of the Chilean Chemical Society; Vol 61, No 4 (2016): Journal of the Chilean Chemical Societyen-US
dc.source0717-9707
dc.subjectSaprophytic fungi; UV-B radiation; Secondary metabolites; Antibacterial properties; Antioxidant activityen-US
dc.titleCHANGES IN SECONDARY METABOLITES PROFILES AND BIOLOGICAL ACTIVITY OF THE FRESH FRUITING BODIES OF Stereum hirsutum EXPOSED TO HIGH-DOSE UV-B RADIATIONen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeen-US


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