A new species, Telmatobufo ignotus, from the Reserva Nacional Los Queules, Cauquenes Province, central Chile is described herein. The new taxon is hypothesized based on a new combination of adult, larval, and chromosomal characters. The new species present the more septentrional distribution on the coastal range and a very restrictive distribution area compared to its congeners; because of this, taxonomic and conservation comments are discussed and advanced.