The objective of the present work is to diminish the total process time (Makespan) and to increase the machine process time, by diminishing the idle time in a job-shop environment. Through the design of a hyper-heuristic based on an ant colony and genetic algorithms. This work is developed in two phases: in the first phase, a hyper-heuristic identification and definition is carried out for sequencing processes in job shop environments. In the second phase, the system effectiveness in the traditional production programming is shown. In the investigation project, an enterprise from the metal mechanic sector was chosen, where by means of a combination of an ant colony and genetic algorithms, the optimal route for an order is scheduled, achieving the optimization or suboptimization of its respective total process time in an upper percentage of 95%.