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dc.creatorDavarian,Ali
dc.creatorFazeli,Seyyed Amirhossein
dc.creatorAzarhoush,Ramin
dc.creatorJafar Golalipour,Mohammad
dc.date2005-01-01
dc.date.accessioned2019-04-25T12:33:58Z
dc.date.available2019-04-25T12:33:58Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000400013
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/59404
dc.descriptionFormaldehyde is a chemical, which is used traditionally for fixing the cadaver. It is vaporized during dissection and practical studying on cadaver. Studies show that this vapor can cause some clinical symptoms such as throat, eye, skin and nasal irritation. This study was designed to determine the histopathologic changes of rat tracheal mucosa while all of the experiments were exposed to formaldehyde for 18 weeks. This study was performed on 28, 6-7 weeks postnatal albino Wistar rats. The rats were divided into 3 case groups (E1: 4h/d, 4d/w; E2: 2h/d, 4d/w; E3: 2h/d, 2d/w) and 1 control group. The tracheal specimens were sectioned and stained with H&E technique for histopathologic study. An epithelial disorganization, cilia disappearance, slight dysplastic changes and slight subepithelial lymphocytic infiltration were observed in the case of E1. Epithelial disorganization, irregular cilia and slight subepithelial infiltration were seen in E2 and E3 groups. The results of this study show that "the more exposure to formaldehyde vapor, the more intense epithelial changes"
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Anatomía
dc.relation10.4067/S0717-95022005000400013
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceInternational Journal of Morphology v.23 n.4 2005
dc.subjectFormaldehyde exposure
dc.subjectRat
dc.subjectTracheal mucosa
dc.titleHistopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure


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