Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles
Author
Issa,Joáo Paulo Mardegan
Nascimento,Cássio do
Sato,Sandra
Barbosa,Rodrigo Edson Santos
Benetti,Emerson Toffanello
Albuquerque Junior,Rubens Ferreira de
Abstract
The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them