Newly Formed Bone in Mandible Decortication Experimental Model Using rhBMP-2 Evaluated by Densitometric Study
Author
Issa,João Paulo Mardegan
Tiossi,Rodrigo
Watanabe,Plauto Christopher Aranha
Siéssere,Selma
Regalo,Simone Cecílio Hallak
Lopes,Ruberval Armando
Di Matteo,Miguel Angel Sala
Iyomasa,Mamie Mizusaki
Defino,Helton Luiz Aparecido
Abstract
The purpose of this study was to evaluate the newly formed bone, comparing two different carriers for rhBMP-2, using the decortication and nondecorticatication surgical technique in Wistar rat mandibles, evaluated by radiographic densitometry method. It was used fifty six animals according to specific treatment, which were sacrificed after 3 and 6 weeks after this. It was concluded that the decortication surgical technique was able to optimize the osteoinduction properties of the rhBMP-2, independently of the material carrier used and the period of time, according to radiographic densitometry technique.