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dc.creatorBernardes,Vanessa Fátima
dc.creatorRamos-Jorge,Maria Letícia
dc.creatorVieira Carmo,Maria Auxiliadora
dc.creatorCardoso,Sérgio Vitorino
dc.creatorAlves Mesquita,Ricardo
dc.creatorFerreira Aguiar,Maria Cássia
dc.date2008-12-01
dc.date.accessioned2019-04-25T12:35:21Z
dc.date.available2019-04-25T12:35:21Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400036
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/59828
dc.descriptionThe association among clinicopathological features and c-erbB-2 oncoprotein expression was evaluated in twenty-nine cases of intra-oral mucoepidermoid carcinoma (MEC). MEC was prevalent in the female gender (79.3%), tumors were more frequent in ages between 21 and 40 years (48.3%), and the palate was the most commonly affected site (72.4%). Microscopically, 27 cases (93.1%) were classified as low grade of malignancy. The c-erbB-2 expression was considered positive in 9 (31%) cases and no significant association (p>0.05) was found among protein expression and gender ñor between patient age and site or histological grade of the lesión. c-erbB-2 expression in MEC may reflect intrisinc biologic properties of salivary gland neoplasms and may be linked to histogenesis and cellular differentiaton.
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Anatomía
dc.relation10.4067/S0717-95022008000400036
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceInternational Journal of Morphology v.26 n.4 2008
dc.subjectc-erbB-2
dc.subjectHer-2/neu
dc.subjectImmunohistochemistry
dc.subjectMucoepidermoid carcinoma
dc.subjectSalivary gland neoplasms
dc.titleIntraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases


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