With recent developments in mobile technologies, tourism mobile payment(m-payment) is beginning to offer interesting and beneficial new services. This research aimed to identify the factors determining tourists’ acceptance of tourism m-payment. Based on literature relating to the TAM theory, the conceptual model is developed and tested in this research. This research extends the applicability of the TAM in tourism m-payment context, by adding the system characteristics’ constructs and tourism characteristics’ constructs to the model. Data collected from 421 tourists in China were tested against the extended TAM, using the structural equation modeling approach. The empirical results show especially strong support for the effects of perceived security, perceived compatibility, destination m-payment knowledge, and tourist susceptibility to interpersonal influence. The findings provide a foundation for an enhanced theory on tourism m-payment adoption and for the practical development of tourism m-payment service.