The paper examines the effect of E-Supply Chain Management Systems in the North American electronics manufacturing services industry. A causal and descriptive research study was conducted based on a survey applied to thirty six individuals in electronic manufacturing services firms in order to determine the impact of e-supply chain management on their key supply chain operations. Results of the research revealed that e-supply chain management had a positive effect in the electronic manufacturing services industry as these showed that the profits of the firm increased and internal communications were improved due to the implementation of e-supply chain management. The research also showed that e-supply chain management systems have many technical issues such as problems with process automation and transmission of supply chain data, e-procurement effectiveness, integration with existing systems and the monitoring of inventory systems and purchasing process. Several recommendations are made to overcome these challenges including employee training and re-engineering of business processes for better system integration.