ABSTRACT: Purpose Zygomatic implants (ZI) constitute a suitable alternative for treating severe maxillary atrophy. However, a large number of complications associated with ZI have been reported in the literature. This paper presents the late complications associated with ZI during 12 years of experience in the same institution. Materials and methods All cases of ZI from 2000 to 2013 were retrospectively evaluated and the major complications relating to this type of rehabilitation were selected to report. Results The major complications found were: loss of implant, loss of osseointegration, bucco-sinusal communication, fenestration of alveolar mucosa, sinus pathology, and emergency palate fixations. Conclusion The clinical experience of the dental surgeon is critical in the success of zygomatic fixation. Furthermore, there should be careful planning of rehabilitation to reduce the rate of complications.