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Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico

dc.creatorCsendes J,Attila
dc.creatorBurdiles P,Patricio
dc.creatorMaluenda G,Fernando
dc.creatorCortés D,Claudio
dc.creatorKorn B,Owen
dc.creatorRojas C,Jorge
dc.creatorTepper J,Patricio
dc.creatorHuertas M,César
dc.creatorSagastume G,Héctor
dc.creatorPuente Q,Guillermo
dc.creatorQuezada M,Fernando
dc.creatorCsendes G,Paula
dc.date1998-07-01
dc.date.accessioned2019-05-02T21:10:31Z
dc.date.available2019-05-02T21:10:31Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98871998000700004
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/80925
dc.descriptionBackground: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in a prospective protocol that included clinical analysis, manometry and endoscopy in all patients, barium swallow in 427, scintigraphy in 195, acid reflux test in 359, 24 h pH in 175, and differential potential of gastroesophageal mucosa in 73 patients. Results: There was no correlation between the severity of symptoms and the endoscopical severity. Patients with Barret esophagus were 12 years older, were male in a greater proportion and had a higher proportion of manometrically incompetent sphincters than patients with esophageal reflux but without esophagitis or with erosive esophagitis. Severity of acid reflux, measured with 24 h pH monitoring was proportional to the endoscopical damage of the mucosa. There was a close relationship between the mucosal change limit determined with differential potentials and with endoscopy. No short esophagi were found. Conclusions: Patients with symptoms of gastroesophageal reflux must be assessed using several objective measures to determine the severity of their pathological alterations.
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dc.languagees
dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98871998000700004
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.126 n.7 1998
dc.subjectEsophageal motility disorders
dc.subjectEsophagitis, peptic
dc.subjectGastro esophageal reflux
dc.subjectManometry
dc.titleCaracterísticas clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico


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