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dc.creatorCuchacovich T,Miguel
dc.creatorHoluigue R,Gloria
dc.creatorGatica R,Héctor
dc.creatorAlvo A,Miriam
dc.creatorMurray T,Guillermo
dc.date2000-01-01
dc.date.accessioned2019-05-02T21:10:42Z
dc.date.available2019-05-02T21:10:42Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000100012
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/81052
dc.descriptionAlthough fibrosis and vasculopathy coexist in most patients with progressive systemic sclerosis, it is not clear if these events are the result of an unique etiologic factor or if one is consequence of the other. We report two cases of progressive systemic sclerosis that evolved to a renal scleroderma crisis. A 36 years old female presented with a Sjögren syndrome and painful subcutaneous nodules whose biopsy showed perivascular lymphocytic infiltration, perivascular thickening and normal skin. The ESR was 100 mm/h. She developed an hypertensive crisis and progressive renal failure, followed by a rapidly evolving progressive systemic sclerosis. The patient died in the course of this crisis. A 32 years old female with a progressive systemic sclerosis refractory to D-penicillamine treatment, receiving cyclosporin, presented a renal scleroderma crisis, that was successfully treated, with complete recovery of renal function. We highlight the different evolution of these cases, probably due to an early diagnosis and a better experience in the management of this condition. (Rev Méd Chile 2000; 128: 86-92)
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dc.languagees
dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872000000100012
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.128 n.1 2000
dc.subjectCyclosporin
dc.subjectKidney failure, acute
dc.subjectPenicillamine
dc.subjectScleroderma, systemic
dc.titleCrisis de esclerodermia renal.: Rol de la vasculopatía esclerodérmica en la inducción de fibrosis cutáneo-visceral en dos casos


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