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dc.creatorBlackburn T,Eileen
dc.creatorMur R,Paola
dc.creatorJofré A,Boris
dc.creatorColl C,Claudia
dc.creatorJurlow M,Elizabeth
dc.date2000-04-01
dc.date.accessioned2019-05-02T21:10:46Z
dc.date.available2019-05-02T21:10:46Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000400003
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/81097
dc.descriptionBackground: Delayed cutaneous hypersensitivity tests are a globally accepted test to assess cellular immunity in vivo. The quality and quantity of the response to these type of tests, varies in different populations. Aim: To study delayed cutaneous hypersensitivity in a group of healthy Chilean elders. Material and methods: Forty two elders (32 male), aged 60 to 76 years old were studied. Multitest-CMI® was applied in the left forearm. This test allows the subcutaneous administration of seven antigens and a glycerin control. Results were compared with those of a group of young adults studied by the authors. Results: Among males there was a mean of 2.7 ± 1.4 positive responses compared with women, that had 1.7 ± 1 positive responses (p= 0.016). The sum of response diameters was 4.2 ± 1.5 and 3.6 ± 1.9 mm in men and women respectively (p = NS). Compared to young adults, elderly women had a lower response to tetanus and diphtheria toxoids and men had a lower response to diphtheria and Proteus mirabilis. Conclusions: Elderly people have a less intense response to delayed cutaneous hypersensitivity tests than young adults. This response must be assessed in each population to account for regional variability. (Rev Méd Chile 2000; 128: 379-86).
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dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872000000400003
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.128 n.4 2000
dc.subjectAged
dc.subjectImmunologic tests
dc.subjectHypersensitivity, delayed
dc.subjectImmunologic surveillance
dc.titleInmunosenescencia: pruebas cutáneas de hipersensibilidad retardada en adultos mayores chilenos autovalentes


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