Carbonic anhydrase activity in the red blood cells of sea level and high altitude natives

dc.creator	GAMBOA,JORGE
dc.creator	CACEDA,RICARDO
dc.creator	GAMBOA,ALFREDO
dc.creator	MONGE-C,CARLOS
dc.date	2000-01-01
dc.date.accessioned	2019-05-02T21:20:59Z
dc.date.available	2019-05-02T21:20:59Z
dc.identifier	https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000300006
dc.identifier.uri	http://revistaschilenas.uchile.cl/handle/2250/81340
dc.description	Red blood cell carbonic anhydrase (CA) activity has not been studied in high altitude natives. Because CA is an intraerythocytic enzyme and high altitude natives are polycythemic, it is important to know if the activity of CA per red cell volume is different from that of their sea level counterparts. Blood was collected from healthy subjects living in Lima (150m) and from twelve subjects from Cerro de Pasco (4330m), and hematocrit and carbonic anhydrase activity were measured. As expected, the high altitude natives had significantly higher hematocrits than the sea level controls (p=0.0002). No difference in the CA activity per milliliter of red cells was found between the two populations. There was no correlation between the hematocrit and CA activity.
dc.format	text/html
dc.language	en
dc.publisher	Sociedad de Biología de Chile
dc.relation	10.4067/S0716-97602000000300006
dc.rights	info:eu-repo/semantics/openAccess
dc.source	Biological Research v.33 n.3-4 2000
dc.subject	Carbonic anhydrase
dc.subject	hypoxia
dc.subject	polycythemia
dc.title	Carbonic anhydrase activity in the red blood cells of sea level and high altitude natives