Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections

dc.creator	SERANI-MERLO,ALEJANDRO
dc.date	2001-01-01
dc.date.accessioned	2019-05-02T21:21:02Z
dc.date.available	2019-05-02T21:21:02Z
dc.identifier	https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000200015
dc.identifier.uri	http://revistaschilenas.uchile.cl/handle/2250/81372
dc.description	The 'slow axoplasmic transport theory' has been the prevailing view over the last forty years in order to explain the metabolic maintenance of neuronal axons and nerve endings. A significant amount of evidence against this theoretic interpretation of the existing experimental data has been presented by J. Alvarez, A. Giuditta and E. Koenig in an exhaustive review. They propose an alternative theoretical interpretation called the 'local synthesis model', integrating recent evidence for axon biology and regeneration. We present some epistemological considerations that reinforce the above criticisms and propositions.
dc.format	text/html
dc.language	en
dc.publisher	Sociedad de Biología de Chile
dc.relation	10.4067/S0716-97602001000200015
dc.rights	info:eu-repo/semantics/openAccess
dc.source	Biological Research v.34 n.2 2001
dc.subject	axon biology
dc.subject	biological epistemology
dc.subject	neuron
dc.subject	slow axonal transport
dc.title	Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections