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dc.creatorBAPTISTA,FRANCIELLE
dc.creatorAVEZUM ALVES DE CASTRO-PRADO,MARIALBA
dc.date2002-01-01
dc.date.accessioned2019-05-02T21:21:08Z
dc.date.available2019-05-02T21:21:08Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300018
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/81443
dc.descriptionThe participation of the recently described uvsZ1 mutation in checkpoint control and the identification of epistatic relations between uvsZ1 mutation and uvsD153 and uvsJ1 mutations are provided. The effect of mutation uvsZ1 in mitotic exchanges into paba-bi (chromosome I) and cho-nic (chromosome VII) genetic intervals has also been evaluated. The mutation uvsZ1 was epistatic with regard to uvsD153 and uvsJ1 mutations, with no involvement with checkpoint control. In contrast to mutations in UvsB and UvsF groups, the uvsZ1 mutation failed to cause any changes in the frequencies of mitotic crossing-over. The distinct phenotypic traits given by mutation uvsZ1 suggest the presence of complex interactions among the different DNA repair pathways. Interaction may be an additional cell strategy of DNA damage response
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602002000300018
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.35 n.3-4 2002
dc.subjectcheckpoint pathways
dc.subjectDNA repair
dc.subjectuvs mutations
dc.titleuvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans


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