| dc.creator | NUNES CHINI,EDUARDO | |
| dc.date | 2004-01-01 | |
| dc.date.accessioned | 2019-05-02T21:21:20Z | |
| dc.date.available | 2019-05-02T21:21:20Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400009 | |
| dc.identifier.uri | http://revistaschilenas.uchile.cl/handle/2250/81541 | |
| dc.description | Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent activator of intracellular Ca2+ release in several vertebrate and invertebrate systems. The role of the NAADP system in physiologicalprocesses is being extensively investigated at the present time. The NAADP receptor and its associated Ca2+ pool have been hypothesized to be important in several physiologicalprocesses including fertilization, T cell activation, and pancreaticsecretion. However, whether NAADP is a new second messenger ora tool for the discovery of a new Ca2+ channel is still an unansweredquestion. Research developed over the last two years has provided some important clues to whether NAADP is or not a physiological cellular messenger. In this short review, I will discuss some of these new findings that are helping us to find an answer to the important question: Is NAADP a second messenger or not? | |
| dc.format | text/html | |
| dc.language | en | |
| dc.publisher | Sociedad de Biología de Chile | |
| dc.relation | 10.4067/S0716-97602004000400009 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Biological Research v.37 n.4 2004 | |
| dc.subject | NAADP | |
| dc.subject | Ca2+ | |
| dc.subject | channels | |
| dc.subject | cADPR | |
| dc.subject | intracellular | |
| dc.subject | second messenger | |
| dc.title | To be or not to be… Nicotinic acid adenine dinucleotide phosphate (NAADP): A new intracellular second messenger? | |
