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dc.creatorGARCÍA,CARLOS
dc.creatorLAGOS,MARCELO
dc.creatorTRUAN,DOMINIQUE
dc.creatorLATTES,KARINNA
dc.creatorVÉJAR,OMAR
dc.creatorCHAMORRO,BEATRIZ
dc.creatorIGLESIAS,VERÓNICA
dc.creatorANDRINOLO,DARÍO
dc.creatorLAGOS,NÉSTOR
dc.date2005-01-01
dc.date.accessioned2019-05-02T21:21:25Z
dc.date.available2019-05-02T21:21:25Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000200009
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/81590
dc.descriptionThis study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 mg/100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract sample
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602005000200009
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.38 n.2-3 2005
dc.subjectparalytic shellfish poisoning
dc.subjectPSP human intoxication
dc.subjectChilean fjords
dc.titleHuman intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine


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