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dc.creatorPÉREZ,JOSÉ M
dc.creatorPRADEÑAS,GONZALO A
dc.creatorNAVARRO,CLAUDIO A
dc.creatorHENRÍQUEZ,DANIEL R
dc.creatorPICHUANTES,SERGIO E
dc.creatorVÁSQUEZ,CLAUDIO C
dc.date2006-01-01
dc.date.accessioned2019-05-02T21:21:34Z
dc.date.available2019-05-02T21:21:34Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000500009
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/81707
dc.descriptionSalmonella entérica serovar Typhimurium cells expressing the cadA gene of Geobacillus stearothermophilus LV exhibit a hypersensitive phenotype to cadmium chloride. Deletion of the ORF STM3576 from the Salmonella genome resulted in cadmium, lead and zinc sensitivity, confirming that this ORF is a homologue of the zntA gene. The observed sensitivity was reverted upon expression of the G. stearothermophilus LV cadA gene. These results indicate that the cadA gene product is involved in Cd, Pb and Zn resistance as a classical P-type ATPase and strongly suggest that the observed hypersensitive phenotype to these metals can be related to the function of the host ·zntA gene product
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602006000500009
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.39 n.4 2006
dc.subjectCadA
dc.subjectcadmium
dc.subjectlead
dc.subjectP-type ATPase
dc.subjectzinc
dc.subjectzntA
dc.titleGeobacillus stearothermophilus LV cadA gene mediates resistance to cadmium, lead and zinc in zntA mutants of Salmonella entérica serovar Typhimurium


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