| dc.creator | Videla,Luis A | |
| dc.date | 2010-01-01 | |
| dc.date.accessioned | 2019-05-02T21:21:57Z | |
| dc.date.available | 2019-05-02T21:21:57Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000300014 | |
| dc.identifier.uri | http://revistaschilenas.uchile.cl/handle/2250/82079 | |
| dc.description | Oxidative stress is an imbalance between pro-oxidants and antioxidants in favor of the pro-oxidants, leading to different responses depending on the level of pro-oxidants achieved and the duration of exposure. In this article, we discuss the cytoprotective or suicidal signaling mechanisms associated with oxidative stress by addressing: (i) the development of an acute and mild pro-oxidant state by thyroid hormone administration eliciting the redox upregulation of the expression of proteins affording cell protection as a preconditioning strategy against ischemia-reperfusion liver injury; and (ii) the role of prolonged and severe oxidative stress and insulin resistance as determinant factors in the pathogenesis of non-alcoholic fatty liver disease associated with obesity. | |
| dc.format | text/html | |
| dc.language | en | |
| dc.publisher | Sociedad de Biología de Chile | |
| dc.relation | 10.4067/S0716-97602010000300014 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Biological Research v.43 n.3 2010 | |
| dc.subject | oxidative stress | |
| dc.subject | thyroid hormone | |
| dc.subject | liver preconditioning | |
| dc.subject | obesity | |
| dc.subject | insulin resistance | |
| dc.subject | non-alcoholic fatty liver disease | |
| dc.title | Cytoprotective and suicidal signaling in oxidative stress | |
