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Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents

dc.creatorMoraes de Carvalho,Katharinne I
dc.creatorFernandes,Hélio B
dc.creatorFrota Machado,Flávia D
dc.creatorOliveira,Irisdalva S
dc.creatorOliveira,Francisco A
dc.creatorNunes,Paulo Humberto M
dc.creatorLima,Julianeli T
dc.creatorSilva Almeida,Jackson R G
dc.creatorMeneses Oliveira,Rita C
dc.date2010-01-01
dc.date.accessioned2019-05-02T21:21:59Z
dc.date.available2019-05-02T21:21:59Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400011
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/82099
dc.descriptionThis study evaluated the antiulcer activity of an ethanolic extract of Encholirium spectabile (ES-EtOH) by using different standard experimental models of induced acute gastric ulceration. ES-EtOH (100 mg/kg p.o) protected the gastric mucosa against ulceration that was induced by absolute ethanol (53%), ethanol/HCl (75 %), ibuprofen (52 %) and ischemia/reperfusion (43 %). It also restored catalase activity and non-protein sulfhydryl group concentration in the gastric wall of mice that had been treated with ethanol. The pre-treatment of mice with N-nitro-L-arginine (70 mg/kg i.p.) abolished the protective activity of ES-EtOH, which indicates that prostaglandins, antioxidant compounds and nitric oxide synthase activity are involved in the gastroprotective activity of the extract.
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602010000400011
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.43 n.4 2010
dc.subjectantioxidant
dc.subjectantiulcer activity
dc.subjectEncholirium spectabile
dc.subjectBromeliaceae
dc.titleAntiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents


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