Location matters: the endoplasmic reticulum and protein trafficking in dendrites

dc.creator	Ramírez,Omar A
dc.creator	Härtel,Steffen
dc.creator	Couve,Andrés
dc.date	2011-01-01
dc.date.accessioned	2019-05-02T21:21:59Z
dc.date.available	2019-05-02T21:21:59Z
dc.identifier	https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000100003
dc.identifier.uri	http://revistaschilenas.uchile.cl/handle/2250/82106
dc.description	Neurons are highly polarized, but the trafficking mechanisms that operate in these cells and the topological organization of their secretory organelles are still poorly understood. Particularly incipient is our knowledge of the role of the neuronal endoplasmic reticulum. Here we review the current understanding of the endoplasmic reticulum in neurons, its structure, composition, dendritic distribution and dynamics. We also focus on the trafficking of proteins through the dendritic endoplasmic reticulum, emphasizing the relevance of transport, retention, assembly of multi-subunit protein complexes and export. We additionally discuss the roles of the dendritic endoplasmic reticulum in synaptic plasticity.
dc.format	text/html
dc.language	en
dc.publisher	Sociedad de Biología de Chile
dc.relation	10.4067/S0716-97602011000100003
dc.rights	info:eu-repo/semantics/openAccess
dc.source	Biological Research v.44 n.1 2011
dc.subject	endoplasmic reticulum
dc.subject	protein trafficking
dc.subject	dendrites
dc.subject	neuron
dc.title	Location matters: the endoplasmic reticulum and protein trafficking in dendrites