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dc.creatorCosta Marques,Thiago H
dc.creatorSantos De Melo,Cassio H
dc.creatorFonseca De Carvalho,Rusbene B
dc.creatorCosta,Luciana M
dc.creatorDe Souza,Alexandre A
dc.creatorDavid,Jorge M
dc.creatorDe Lima David,Juceni P
dc.creatorDe Freitas,Rivelilson M
dc.date2013-01-01
dc.date.accessioned2019-05-02T21:22:12Z
dc.date.available2019-05-02T21:22:12Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300002
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/82317
dc.descriptionThis study describes the isolation and identification of apigenin-7-O-ghicopyranoside, a flavonoid isolated from the flowers of Bellis perennis L., Asteraceae, an species with a broad spectrum of biological activities. The in vitro antioxidant activity and the inhibition of the enzyme acetylcholinesterase were evaluated. The flavonoid showed strong in vitro antioxidant potential, because of the capacity of removal of hydroxyl radicals and nitric oxide, and also prevented the formation of thiobarbituric acid-reactive substances. These parameters were inhibited at the highest concentration of ApG at rates of 77.7%, 72% and 73.4%, respectively, in addition to inhibiting acetylcholinesterase, suggesting potential use in the treatment of neurodegenerative diseases.
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602013000300002
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.46 n.3 2013
dc.subjectAcetylcholinesterase
dc.subjectAntioxidant
dc.subjectBellis perennis
dc.subjectFlavonoid
dc.titlePhytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis


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