| dc.creator | García-Labastida,Laura | |
| dc.creator | Garza-Guajardo,Raquel | |
| dc.creator | Barboza-Quintana,Oralia | |
| dc.creator | Rodríguez-Sanchez,Irám Pablo | |
| dc.creator | Ancer-Rodríguez,Jesús | |
| dc.creator | Flores-Gutierrez,Juan Pablo | |
| dc.creator | Gómez-Macías,Gabriela Sofía | |
| dc.date | 2014-01-01 | |
| dc.date.accessioned | 2019-05-02T21:22:19Z | |
| dc.date.available | 2019-05-02T21:22:19Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100043 | |
| dc.identifier.uri | http://revistaschilenas.uchile.cl/handle/2250/82403 | |
| dc.description | BACKGROUND: Pure mucinous adenocarcinoma of the breast is a rare entity characterized by the production of variable amounts of mucin comprising 1% to 6% of breast carcinomas. Some mucinous adenocarcinomas have shown expression of intestinal differentiation markers such as MUC-2. This study examines the expression of intestinal differentiation markers in this type of breast carcinoma. RESULTS: Twenty-two cases of pure mucinous adenocarcinoma of the breast were assessed. Immunochemistry was performed for beta-catenin, CDX-2 and MUC-2. All cases were positive for B-catenin. MUC-2 positivity was observed in all cases; 63. 6% were 3 plus positive. All cases were negative for CDX-2. CONCLUSIONS: These results suggest that mucinous breast carcinomas express some markers of intestinal differentiation, such as MUC-2 and beta-catenin; however, future studies with a larger series of cases and using molecular techniques that help affirm these results are needed. | |
| dc.format | text/html | |
| dc.language | en | |
| dc.publisher | Sociedad de Biología de Chile | |
| dc.relation | 10.1186/0717-6287-47-43 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Biological Research v.47 2014 | |
| dc.subject | Breast mucinous carcinoma | |
| dc.subject | Inmunohistochemical | |
| dc.subject | Intestinal differentiation | |
| dc.title | CDX-2, MUC-2 and B-catenin as intestinal markers in pure mucinous carcinoma of the breast | |
