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dc.creatorShao,Jin
dc.creatorZhang,Weiwei
dc.creatorYang,Tieyi
dc.date2015-01-01
dc.date.accessioned2019-05-02T21:22:31Z
dc.date.available2019-05-02T21:22:31Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100062
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/82598
dc.descriptionBone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and differentiate into either chondroblasts or osteoblasts precursors, leading to bone repairing and regeneration. Besides these two precursors, the MSCs can also differentiate into adipocyte precursors, skeletal muscle precursors and some other mesodermal cells. With this multiline-age potentiality, the MSCs are probably used to cure bone injury and other woundings in the near future. Here we will introduce the recent developments in understanding the mechanism of MSCs action in bone regeneration and repairing.
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.1186/S40659-015-0053-4
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.48 2015
dc.subjectMesenchymal stem cells
dc.subjectBone regeneration
dc.subjectBone repairing
dc.subjectTissue engineering
dc.titleUsing mesenchymal stem cells as a therapy for bone regeneration and repairing


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