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dc.creatorMurray,Nigel P.
dc.date2018-01-01
dc.date.accessioned2019-05-02T21:22:45Z
dc.date.available2019-05-02T21:22:45Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602018000100503
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/82782
dc.descriptionAbstract Minimal residual disease is that not detected by conventional imaging studies and clinically the patient remains disease free. However, with time these dormant cells will awaken and disease progression occurs, resulting in clinically and radiological detectable metastatic disease. This review addresses the concept of tumor cell dissemination from the primary tumor, the micrometastatic niche and tumor cell survival and finally the clinical utility of detecting and characterizing these tumor cells in order to guide management decisions in treating patients with prostate cancer.
dc.formattext/html
dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.1186/s40659-018-0180-9
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.51 2018
dc.subjectProstate cancer
dc.subjectCirculating tumor cells
dc.subjectTumor cell dissemination
dc.subjectDormancy
dc.subjectMicrometastasis
dc.subjectPhenotype
dc.subjectTreatment
dc.titleMinimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management


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