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dc.creatorSong,Le
dc.creatorCruz,Caroline
dc.creatorFarrah,Samuel R
dc.creatorBaney,Ronald H
dc.date2009-04-01
dc.date.accessioned2019-05-03T12:44:37Z
dc.date.available2019-05-03T12:44:37Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-34582009000200013
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/85070
dc.descriptionA significant effort worldwide is being directed toward development of novel biocides against drug-resistant bacterial and viruses because of the significant potential human infection risks in the general population. We report here the discovery of a strong antiviral biocide, dialdheyde starch (DAS). Antiviral tests were carried out against three non-envelop viruses, including two bacterial viruses MS2 and PRD1, and one human virus Poliovirus. Dialdehyde starch aqueous suspensions were effective biocides against these three test viruses in a 1 hr exposure test. The antiviral activity was significantly enhanced in a four-hour exposure test, with maximum seven orders of magnitude reductions against MS2 and PRD1, and four-order reduction against Poliovirus. The antiviral activity of dialdehyde starch was found to be pH dependent, being more active in alkaline and acidic conditions than in neutral conditions.
dc.formattext/html
dc.languageen
dc.publisherPontificia Universidad Católica de Valparaíso
dc.relation10.4067/S0717-34582009000200013
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceElectronic Journal of Biotechnology v.12 n.2 2009
dc.subjectantiviral
dc.subjectbiocide
dc.subjectdialdehyde starch
dc.subjectvirus
dc.titleNovel antiviral activity of dialdehyde starch


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