dc.creator | Song,Le | |
dc.creator | Cruz,Caroline | |
dc.creator | Farrah,Samuel R | |
dc.creator | Baney,Ronald H | |
dc.date | 2009-04-01 | |
dc.date.accessioned | 2019-05-03T12:44:37Z | |
dc.date.available | 2019-05-03T12:44:37Z | |
dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-34582009000200013 | |
dc.identifier.uri | http://revistaschilenas.uchile.cl/handle/2250/85070 | |
dc.description | A significant effort worldwide is being directed toward development of novel biocides against drug-resistant bacterial and viruses because of the significant potential human infection risks in the general population. We report here the discovery of a strong antiviral biocide, dialdheyde starch (DAS). Antiviral tests were carried out against three non-envelop viruses, including two bacterial viruses MS2 and PRD1, and one human virus Poliovirus. Dialdehyde starch aqueous suspensions were effective biocides against these three test viruses in a 1 hr exposure test. The antiviral activity was significantly enhanced in a four-hour exposure test, with maximum seven orders of magnitude reductions against MS2 and PRD1, and four-order reduction against Poliovirus. The antiviral activity of dialdehyde starch was found to be pH dependent, being more active in alkaline and acidic conditions than in neutral conditions. | |
dc.format | text/html | |
dc.language | en | |
dc.publisher | Pontificia Universidad Católica de Valparaíso | |
dc.relation | 10.4067/S0717-34582009000200013 | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.source | Electronic Journal of Biotechnology v.12 n.2 2009 | |
dc.subject | antiviral | |
dc.subject | biocide | |
dc.subject | dialdehyde starch | |
dc.subject | virus | |
dc.title | Novel antiviral activity of dialdehyde starch | |