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dc.creatorBouguettoucha,Abdallah
dc.creatorBalannec,Béatrice
dc.creatorNacef,Saci
dc.creatorAmrane,Abdeltif
dc.date2010-09-01
dc.date.accessioned2019-05-03T12:44:44Z
dc.date.available2019-05-03T12:44:44Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000500007
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/85148
dc.descriptionAn unstructured model for growth and lactic acid production during two-stage continuous cultures of Lactobacillus helveticus was previously developed. The Verlhust model was considered to describe growth kinetics. Production models was based on modified Luedeking-Piret expressions involving an inhibitory effect for the first stage (seed culture) and a nutritional limitation effect for the second stage (culture). To account for the decrease of the biomass concentration observed in the second stage, the dilution rate Dc was replaced by an exponential term of the dilution rate <img border=0 width=84 height=36 src="http://fbpe/img/ejb/v13n5/a07/image002.gif" align=middle>in the growth and product relations. Contrarily to the previous model, the important decrease of the biomass concentration observed at steady state in the second stage at high dilution rates, namely close to wash out, was correctly described by the new model. It also proved to satisfactory describes production data and volumetric productivity.
dc.formattext/html
dc.languageen
dc.publisherPontificia Universidad Católica de Valparaíso
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceElectronic Journal of Biotechnology v.13 n.5 2010
dc.subjectcontinuous culture
dc.subjectgrowth
dc.subjectlactic acid fermentation
dc.subjectsubstrate limitation
dc.subjectunstructured models
dc.titleImproved growth model for two-stage continuous cultures of Lactobacillus helveticus


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