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Modeling of glutamic acid production by Lactobacillus plantarum MNZ

dc.creatorZareian,Mohsen
dc.creatorEbrahimpour,Afshin
dc.creatorMohamed,Abdul Karim Sabo
dc.creatorSaari,Nazamid
dc.date2013-07-01
dc.date.accessioned2019-05-03T12:45:06Z
dc.date.available2019-05-03T12:45:06Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000400012
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/85359
dc.descriptionBackground: L-glutamic acid, the principal excitatory neurotransmitter in the brain and an important intermediate in metabolism acts as a precursor of γ-amino butyric acid (GABA). In the present study, culture condition for enhanced glutamic acid production by Lactobacillus plantarum MNZ was optimized and the influence of such conditions on GABA production was evaluated. Results: Results indicated that glutamic acid increased up to 3-fold (3.35) under the following condition: pH 4.5, temperature 37ºC, 12% (w/v) glucose and 0.7% (w/v) ammonium nitrate; whilst GABA production was enhanced up to 10-fold under the following condition: pH 4.5, temperature 37ºC, 6% (w/v) glucose and 0.7% (w/v) ammonium nitrate. Conclusions: This is the first report for dual biosynthesizing activities of a lactic acid bacterium for the production of glutamic acid and GABA. The results of this study can be further used for developing functional foods rich inglutamic acid and subsequently GABA as a bioactive compound.
dc.formattext/html
dc.languageen
dc.publisherPontificia Universidad Católica de Valparaíso
dc.relation10.2225/vol16-issue4-fulltext-10
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceElectronic Journal of Biotechnology v.16 n.4 2013
dc.subjectγ-amino butyric acid
dc.subjectfunctional foods
dc.subjectlactic acid bacteria
dc.subjectmedium optimization
dc.subjectresponse surface methodology
dc.titleModeling of glutamic acid production by Lactobacillus plantarum MNZ


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