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dc.creatorLee,Youngsub
dc.creatorPark,Sairom
dc.creatorKim,Hun
dc.creatorLee,Seung Kyu
dc.creatorKim,Jin Woo
dc.creatorLee,Hak Kyo
dc.creatorJeong,Dong Kee
dc.creatorLee,Sung Jin
dc.date2013-09-01
dc.date.accessioned2019-05-03T12:45:08Z
dc.date.available2019-05-03T12:45:08Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000500014
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/85374
dc.descriptionBackground: The melanocortin-4 receptor gene (MC4R) plays an important role in regulating food intake and body weight in mammals. In the present study, we identified the MC4R gene in native Korean brown, brindle, and black cattle by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP), and investigated its association with economic traits. A total of 413 cattle from the three breeds were tested for backfat thickness, carcass weight, longissimus muscle area, and marbling score, and statistical data were analyzed using the SAS program. Results: The C allele had the highest frequency in brown and brindle cattle, and the G allele frequency was highest in black cattle. The C1069G SNP was significantly (p < 0.05) associated with only marbling scores in brown and brindle cattle but no significant association was detected between the marbling scores and polymorphism in black cattle. Conclusions: These results suggest that a C1069G SNP of the MC4R gene may be useful as a genetic marker for marbling scores in Korean brown and brindle cattle.
dc.formattext/html
dc.languageen
dc.publisherPontificia Universidad Católica de Valparaíso
dc.relation10.2225/vol16-issue5-fulltext-5
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceElectronic Journal of Biotechnology v.16 n.5 2013
dc.subjecteconomic trait
dc.subjectmarbling scores
dc.subjectMC4R gene
dc.subjectPCR-RFLP
dc.subjectSNP
dc.titleA C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)


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