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Strategy of oxygen transfer coefficient control on the L-erythrulose fermentation by newly isolated Gluconobacter kondonii

dc.creatorPan,Long
dc.creatorFang,Ya-kun
dc.creatorZhou,Pei
dc.creatorJin,Kui-qi
dc.creatorGang,Wang
dc.creatorLiu,Yu-peng
dc.date2016-11-01
dc.date.accessioned2019-05-03T12:45:27Z
dc.date.available2019-05-03T12:45:27Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-34582016000600004
dc.identifier.urihttp://revistaschilenas.uchile.cl/handle/2250/85578
dc.descriptionBackground: The effect of diverse oxygen transfer coefficient on the L-erythrulose production from meso-erythritol by a newly isolated strain, Gluconobacter kondonii CGMCC8391 was investigated. In order to elucidate the effects of volumetric mass transfer coefficient (K La) on the fermentations, baffled and unbaffled flask cultures, and fed-batch cultures were developed in present work. Results: With the increase of the K La value in the fed-batch culture, L-erythrulose concentration, productivity and yield were significantly improved, while cell growth was not the best in the high K La. Thus, a two-stage oxygen supply control strategy was proposed, aimed at achieving high concentration and high productivity of L-erythrulose. During the first 12 h, Klawas controlled at 40.28 h-1 to obtain high value for cell growth, subsequently K La was controlled at 86.31 h-1 to allow for high L-erythrulose accumulation. Conclusions: Under optimal conditions, the L-erythrulose concentration, productivity, yield and DCW reached 207.9 ± 7.78 g/L, 6.50 g/L/h, 0.94 g/g, 2.68 ± 0.17 g/L, respectively. At the end of fermentation, the L-erythrulose concentration and productivity were higher than those in the previous similar reports.
dc.formattext/html
dc.languageen
dc.publisherPontificia Universidad Católica de Valparaíso
dc.relation10.1016/j.ejbt.2016.08.006
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceElectronic Journal of Biotechnology v.19 n.6 2016
dc.subjectK La
dc.subjectIndustrial biotechnology
dc.subjectProcess control
dc.subjectProduction
dc.subjectTanning agents
dc.subjectTanning properties
dc.subjectArtificial tanning
dc.subjectDihydroxypropanone (DHA)
dc.subjectProduction of L-erythrulose
dc.subjectMeso-erythritol
dc.subjectBiosynthesis of L-erythrulose
dc.titleStrategy of oxygen transfer coefficient control on the L-erythrulose fermentation by newly isolated Gluconobacter kondonii


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