Today firm’s competitiveness depends on the development of proprietary technology and its integration to commercial technological products. Experiences and case studies show that the micro, small and medium firms (MIPYMES, in Spanish) develop technological products collaborating with public universities. In this work it is presented the colaborative technological product development process phases focusing in the identification of the diverse obstacles occurring along the process. Diverse technical, organizational and communication aspects that affects the project development are discussed. The resistances or barriers to the development make it difficult and could cause project abandon sometimes. This empirical and exploratory research is conducted under the reference of the technological project management model developed and used at the Centro de Ciencias Aplicadas y Desarrollo Tecnológico (CCADET) of the Universidad Nacional Autónoma de México (UNAM).Hoy en día se sabe que la competitividad de las empresas depende del desarrollo de tecnologías propietarias y de su integración a productos tecnológicos comercializables. Muchas experiencias y estudios de caso demuestran que las MIPYMES desarrollan productos tecnológicos colaborando con las universidades públicas. En este trabajo se presenta una revisión de las fases del proceso de desarrollo de productos tecnológicos colaborativo poniendo énfasis en la identificación de los diversos obstáculos que se presentan a lo largo del mismo. Se discuten diversos aspectos técnicos, organizacionales y de comunicación que afectan al proceso convirtiéndose en resistencias o barreras que lo obstaculizan y que pueden llegar inclusive a provocar su abandono. Esta investigación empírica y exploratoria se enfoca desde la perspectiva del modelo de Gestión Tecnológica de Proyectos (GTP) que se lleva a cabo en el Centro de Ciencias Aplicadas y Desarrollo tecnológico, CCADET de la Universidad Nacional Autónoma de México, UNAM.Today firm’s competitiveness depends on the development of proprietary technology and its integration to commercial technological products. Experiences and case studies show that the micro, small and medium firms (MIPYMES, in Spanish) develop technological products collaborating with public universities. In this work it is presented the colaborative technological product development process phases focusing in the identification of the diverse obstacles occurring along the process. Diverse technical, organizational and communication aspects that affects the project development are discussed. The resistances or barriers to the development make it difficult and could cause project abandon sometimes. This empirical and exploratory research is conducted under the reference of the technological project management model developed and used at the Centro de Ciencias Aplicadas y Desarrollo Tecnológico (CCADET) of the Universidad Nacional Autónoma de México (UNAM).