The main objective of this paper is to analyse the impact of gender in adopting and using new information and communication technologies (ICTs) in Spain. It is widely accepted that men tend to be the first to use new technologies and to gain significant benefits from doing so, both at home and work. However, further research on gender and new technologies, such as ICTs, is still needed in order to better understand differences between men and women. On the one hand we show that percentage of ICTs users is higher among men. On the other hand, our results confirm that women also present lower frequency of ICTs use. We examine how the differences in adoption and use of ICTs are moderated by cultural and socioeconomic aspects. Differences appear mainly in the lower levels of education and in the rural area. Therefore, it highlights the necessity of taking into account those aspects to remove the gender digital divide totally. We also underline the importance of changes in gender roles and the increase of the participation of women in the Spanish labour force.