El segmento del Batolito Norpatagonico comprendido entre los 44 y 45ºS esta afectado por una intensa deformacion fragil y ductil localizada en zonas de cizalle, asociada espacialmente a la Zona de Falla Liquine-Ofqui. Esta zona de falla esta representada regionalmente, por un lineamiento de azimut nor-noreste (Canal de Puyuguapi), que, segun estudios anteriores, forma parte de un duplex de rumbo a escala cortical en la Cordillera Patagonica. La deformacion ductil (Mioceno Superior-Plioceno) esta documentada por zonas de milonita tabulares de ancho centimetrico a metrico, con foliacion subvertical y lineacion de estiramiento noreste, mientras que la deformacion transtensional dextral se manifiesta a lo largo de zonas de cizalle este-oeste a noreste. La deformacion fragil (post-Mioceno Superior), representada por fallas decametricas con estrias y buenos indicadores cinematicos, tiene una distribucion areal mas amplia y se sobreimpone a la fabrica ductil. Su cinematica es compatible con un regimen dextral transpresional y transtensional a lo largo de zonas de falla de direcciones nor-noreste y este-noreste, respectivamente. El analisis cinematico de movimientos contemporaneos de rumbo, en el manteo y oblicuos de la deformacion fragil-ductil en los 44-45ºS, sugiere algun grado de particion de esta en un regimen global de transpresion dextral en la Zona de Falla Liquine-Ofqui.Dextral transpression and deformation partitioning in the Liquiñe-Ofqui Fault Zone, Aisén, Chile (44-45ºS). The segment of the North Patagonian Batholith between 44 and 45ºS is affected by locally intense ductile and brittle deformation spatially associated with the Liquiñe-Ofqui Fault Zone. The fault zone, at the regional scale, is representad by a north to northeast-trending lineament (Puyuguapi Canal) which makes up part of a crustal-scale strike-slip duplex in the Patagonian Cordillera as suggested by previous studies. Late Miocene-Pliocene ductile deformation is documented by centimetric-to metric-wide tabular mylonite zones with subvertical foliation and subvertical, oblique, and subhorizontally plunging lineations. Dextral transpressional deformation predominates along north to northeast-trending shear zones, whereas dextral transtensional deformation is documented along east to northeast trending shear zones. Brittle deformation, representad by decametric faults with striae and good kinematic indicators, is widely exposed and overprints the early ductile fabric. The post-Late Miocene brittle deformation is compatible with dextral transpressional and transtensional kinematics along north-northeast and east-northeast fault zones, respectively. A kinematic analysis of contemporaneous strike-slip, oblique-slip and contractional deformation on brittle faults and shear zones at 44ºS, suggests some degree of deformation partitioning of bulk dextral transpressional deformation in the Liquiñe-Ofqui Fault Zone.