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dc.creatorHerrera,Christian L
dc.creatorAlvear,Marysol
dc.creatorBarrientos,Leticia
dc.creatorMontenegro,Gloria
dc.creatorSalazar,Luis A
dc.date2010-04-01
dc.date.accessioned2019-05-17T13:11:25Z
dc.date.available2019-05-17T13:11:25Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0718-16202010000100007
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/97940
dc.descriptionPropolis has been used in traditional medicine for many centuries because of its benefcial health properties, including its antimicrobial capacity. Prosthesis stomatitis affects a signifcant percentage of users of removable dentures; Candida albicans is the most common fungal species associated with the development of this pathology. Thus, the objectives of this study were: a. To evaluate the antifungal activity of six commercial propolis extracts against Candida spp. that was isolated from the oral cavity of removable dentures users, and b. To determine chemical characteristics of the propolis extracts evaluated. Among the results, we note that these concentrations of polyphenols varied between 9 ± 0.3 and 85 ± 2.1 mg mL-1. Chromatographic analysis was able to detect 35 compounds, among which were caffeic acid, myricetin, quercetin, kaempferol, apigenin, pinocembrin, galangin, and caffeic acid phenyl ester (CAPE). All strains tested were inhibited by the liquid extracts of propolis. The MID ranged between 1:40 and 1:1280, and the MIC for C. albicans ranged from 197 µg mL-1 to 441 µg mL-1. From the results obtained in this investigation, we can conclude that all propolis extracts evaluated are capable of inhibiting the development of Candida spp. However, they show signifcant differences in the concentration of polyphenols present and in antifungal activity.
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dc.languageen
dc.publisherPontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería Forestal
dc.relation10.4067/S0718-16202010000100007
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceCiencia e investigación agraria v.37 n.1 2010
dc.subjectAntifungal activity
dc.subjectCandida albicans
dc.subjectpropolis
dc.titleThe antifungal effect of six commercial extracts of Chilean propolis on Candida spp


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