| dc.creator | Soza R,Alejandro | |
| dc.creator | Riquelme P,Fernando | |
| dc.creator | Alvarez L,Manuel | |
| dc.creator | Duarte G,Ignacio | |
| dc.creator | Glasinovic R,Juan Carlos | |
| dc.creator | Arrese J,Marco | |
| dc.date | 1999-12-01 | |
| dc.date.accessioned | 2019-09-10T12:38:57Z | |
| dc.date.available | 2019-09-10T12:38:57Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001200011 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/104905 | |
| dc.description | We report a 72 years old diabetic male that, after the use of combined amoxicillin-clavulanic acid, developed pruritus and jaundice. Liver function tests showed serum total bilirubin of 4.3 mg/dL aspartate aminotransferase 140 U/l (normal <35 U/L), alanine aminotransferase 470 U/L (normal <40) and alkaline phosphatases of 400 U/L (normal <100). Serology for hepatitis A, B and C viruses was negative, ERCP showed a normal biliary tree and liver biopsy disclosed a cholestatic hepatitis. Ursodeoxycholic was started to relieve pruritus. Liver function tests improved shortly thereafter, suggesting that this drug may be useful in the treatment of drug induced cholestasis. | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.relation | 10.4067/S0034-98871999001200011 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista médica de Chile v.127 n.12 1999 | |
| dc.subject | Amoxicillin | |
| dc.subject | Cholestasis, intrahepatic | |
| dc.subject | Clavulanic acids | |
| dc.subject | Hepatitis, toxic | |
| dc.subject | Ursodeoxycholic acid | |
| dc.title | Hepatotoxicidad por amoxicilina/ácido clavulánico: caso clínico | |
