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dc.creatorSoza R,Alejandro
dc.creatorRiquelme P,Fernando
dc.creatorAlvarez L,Manuel
dc.creatorDuarte G,Ignacio
dc.creatorGlasinovic R,Juan Carlos
dc.creatorArrese J,Marco
dc.date1999-12-01
dc.date.accessioned2019-09-10T12:38:57Z
dc.date.available2019-09-10T12:38:57Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98871999001200011
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/104905
dc.descriptionWe report a 72 years old diabetic male that, after the use of combined amoxicillin-clavulanic acid, developed pruritus and jaundice. Liver function tests showed serum total bilirubin of 4.3 mg/dL aspartate aminotransferase 140 U/l (normal <35 U/L), alanine aminotransferase 470 U/L (normal <40) and alkaline phosphatases of 400 U/L (normal <100). Serology for hepatitis A, B and C viruses was negative, ERCP showed a normal biliary tree and liver biopsy disclosed a cholestatic hepatitis. Ursodeoxycholic was started to relieve pruritus. Liver function tests improved shortly thereafter, suggesting that this drug may be useful in the treatment of drug induced cholestasis.
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dc.languagees
dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98871999001200011
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.127 n.12 1999
dc.subjectAmoxicillin
dc.subjectCholestasis, intrahepatic
dc.subjectClavulanic acids
dc.subjectHepatitis, toxic
dc.subjectUrsodeoxycholic acid
dc.titleHepatotoxicidad por amoxicilina/ácido clavulánico: caso clínico


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