Show simple item record

dc.creatorImoto Egami,Mizue
dc.creatorRégis Silva,Maria Regina
dc.creatorComodo Segreto,Helena Regina
dc.creatorAraújo Segreto,Roberto
dc.creatorRodrigues de Paiva,Elias
dc.date1997-01-01
dc.date.accessioned2019-09-10T12:40:36Z
dc.date.available2019-09-10T12:40:36Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-98681997000200005
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/105947
dc.descriptionTaking into account the great sensitivity of the intestinal mucosa to X irradiation we aimed at investigating the radioprotection afforded by the S-2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) on the mice rectum exposed to a single whole body X ray dose of 7 Gy and sacrificed at 1, 3, 6 and 10 days after irradiation. Comparing the data of protected group with those of the unprotected one the following features were observed in the first one: statistically significant increase of both crypt cells per crypt (CrC/Cr) at 1, 3, 6 and 10 days after irradiation and of mitotic figures per crypt (MF/Cr) at 3, 6 and 10 days post exposure. In this way it became clear that these morphometric parameters allowed the estimation of WR2721 rectum protection through the crypt cellularity and epithelial cell kinetics
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Anatomía
dc.relation10.4067/S0716-98681997000200005
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista chilena de anatomía v.15 n.2 1997
dc.subjectMouse
dc.subjectRectum
dc.subjectRadioprotector
dc.titleWR2721 INTESTINAL RADIOPROTECTION: MORPHOMETRICAL ANALYSIS


This item appears in the following Collection(s)

Show simple item record