| dc.creator | Imoto Egami,Mizue | |
| dc.creator | Régis Silva,Maria Regina | |
| dc.creator | Comodo Segreto,Helena Regina | |
| dc.creator | Araújo Segreto,Roberto | |
| dc.creator | Rodrigues de Paiva,Elias | |
| dc.date | 1997-01-01 | |
| dc.date.accessioned | 2019-09-10T12:40:36Z | |
| dc.date.available | 2019-09-10T12:40:36Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-98681997000200005 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/105947 | |
| dc.description | Taking into account the great sensitivity of the intestinal mucosa to X irradiation we aimed at investigating the radioprotection afforded by the S-2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) on the mice rectum exposed to a single whole body X ray dose of 7 Gy and sacrificed at 1, 3, 6 and 10 days after irradiation. Comparing the data of protected group with those of the unprotected one the following features were observed in the first one: statistically significant increase of both crypt cells per crypt (CrC/Cr) at 1, 3, 6 and 10 days after irradiation and of mitotic figures per crypt (MF/Cr) at 3, 6 and 10 days post exposure. In this way it became clear that these morphometric parameters allowed the estimation of WR2721 rectum protection through the crypt cellularity and epithelial cell kinetics | |
| dc.format | text/html | |
| dc.language | en | |
| dc.publisher | Sociedad Chilena de Anatomía | |
| dc.relation | 10.4067/S0716-98681997000200005 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista chilena de anatomía v.15 n.2 1997 | |
| dc.subject | Mouse | |
| dc.subject | Rectum | |
| dc.subject | Radioprotector | |
| dc.title | WR2721 INTESTINAL RADIOPROTECTION: MORPHOMETRICAL ANALYSIS | |
