ACTION OF ALL-TRANS-RETINOIC ACID ON THE FLOOR OF THE MOUTH STRUCTURES OF RAT FETUSES
Author
Gomes Totti,Valéria Maria
Lopes,Ruberval A.
Semprini,Marisa
Sala,Miguel A.
de Mattos,Maria da Glória C.
Watanabe,Ii-Sei
Vieira da Costa,José Renán
Abstract
The objective of the present study was to characterize morphologically, morphometrically and stereologically the epithelial changes in the floor of the mouth of fetuses from rats that received all-trans-retinoic acid during pregnancy. The results suggest that all-trans-retinoic acid causes the appearance of malformed immature and less developed fetuses