| dc.creator | Sánchez D,Ignacio | |
| dc.creator | Alvarez G,Cecilia | |
| dc.creator | Clavería R,Cristián | |
| dc.creator | Lisboa B,Carmen | |
| dc.date | 2001-11-01 | |
| dc.date.accessioned | 2019-09-10T12:41:08Z | |
| dc.date.available | 2019-09-10T12:41:08Z | |
| dc.identifier | https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872001001100006 | |
| dc.identifier.uri | https://revistaschilenas.uchile.cl/handle/2250/106281 | |
| dc.description | Background: There are changes in inspiratory breath sound intensity in patients with airway obstruction. Airway narrowing may change sound spectral characteristics. Aim: To define the characteristics of lung sounds at standardized air flow during methacholine challenge and to compare acoustic changes with transcutaneous oxygen tension (PtcO2) during induced airway narrowing. Patients and methods: Forty asthmatic children (20 male) aged 5.2±1 years and 40 normal children (18 male), aged 5.6 ± 1 years were studied. All patients were free of respiratory tract infections one month before the study. A methacholine challenge from 0.06 to 8 mg/ml was performed; the test was ended when a fall in PtcO2 of >20% from baseline was observed or if the final concentration was reached. Subjects breathed through a pneumotachograph aiming at flows of 0.4 to 0.6 l/s. Respiratory sounds were recorded using contact sensors at the suprasternal notch and at the posterior right lower lobe. From average spectra, power at low (100-200 Hz=P1) and high frequencies (400-2000 =P2) was calculated. Frequencies below which 50% (F50) and 99% (SEF90) of the spectral power between 100 and 2000 Hz was contained, were also calculated. Results: In asthmatics, the metacholine concentration at which a 20% fall in PtcO2 was observed, was lower than in normal children (p< 0.05). There was an increase in P1 (p<0.01) and a reduction in P2 (p<0.01) during inspiration, in subjects that experienced a 20% reduction in PtcO2. Also, there was an increase in F50 and SEF99 during inspiration in lung sounds, but not over the trachea. Conclusions: Lung sounds analysis can be useful for the assessment of airway reactivity in asthmatic children (Rev Méd Chile 2001; 129: 1271-8) | |
| dc.format | text/html | |
| dc.language | es | |
| dc.publisher | Sociedad Médica de Santiago | |
| dc.relation | 10.4067/S0034-98872001001100006 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.source | Revista médica de Chile v.129 n.11 2001 | |
| dc.subject | Asthma | |
| dc.subject | Anti-asthmatic agents | |
| dc.subject | Lung diseases, obstructive | |
| dc.subject | Methacholine chloride | |
| dc.title | Análisis computacional de los ruidos respiratorios en la evaluación de la obstrucción bronquial en niños pequeños que no colaboran con las pruebas espirométricas | |
