I prefer not to comment on Professor Serani's epistemological and methodological objections, as I find they do not apply to my work from the perspective of a reading that recognizes the differences between his metaphysical position and my own. Neither the introduction nor the book itself constitute a philosophical thesis, as they emerge in a metaphysical position that neither seeks nor requires transcendental arguments to justify it. It is either validated or not by the operational coherencies of the observer's life experiences. There is no doubt that I believe that the book does what it sets out to do: it shows the conditions of the constitution of living beings and the conditions of their survival.