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dc.creatorSalazar C,Teresa E
dc.creatorMéricq,M Verónica
dc.creatorEspinoza F,Marcela
dc.creatorIñiguez V,Germán
dc.creatorCarvallo de SQ,Pilar
dc.creatorCassorla G,Fernando
dc.date2001-04-01
dc.date.accessioned2019-09-10T12:42:48Z
dc.date.available2019-09-10T12:42:48Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872001000400006
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/107353
dc.descriptionCirculating concentrations of the high affinity growth hormone binding protein (GHBP) may be a marker of GH receptor density as well as GH sensiffvity. Goal: To determine values of GHBP for a normal Chilean pediatric population. Methods: We determined GHBP levels in 73 males and 73 females between 4 to 15.5 years and 4 to 16.8 years respectively, divided in 7 groups according to age and puberal status. Results: The population was normally distributed in weight, height and body mass index (BMI). GHBP activity increased up to Tanner IV in males and Tanner III in females, and decreased slightly thereafter in Tanner V and IV respectively. There was a significant difference between GHBP levels of preschool children and those found in Tanner II to V in both sexes (p<0.05). In adition, we found a positive correlation between GHBP vs weight, height and BMI (p<0.001) in males and females. Conclusion: The availability of this methodology allows us to establish the normative value of GHBP in our population and provides useful information to interpret GH circulating levels in children with growth disorders.(Rev Méd Chile 2001; 129: 382-9)
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dc.publisherSociedad Médica de Santiago
dc.relation10.4067/S0034-98872001000400006
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista médica de Chile v.129 n.4 2001
dc.subjectGrowth
dc.subjectPediatrics
dc.subjectSomatotropin
dc.subjectSomatropin
dc.titleValores de referencia para proteína transportadora de hormona de crecimiento en una población pediátrica normal


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