Déficit Adquirido de factor X en leucemia mielomonocítica crónica: reporte de un caso

Déficit Adquirido de factor X en Leucemia mielomonocítica crónica: reporte de un caso

Author
Zelada, Javier; HOSPITAL CLINICO DE LA FUERZA AEREA DE CHILE

Cantó, Gabriela; HOSPITAL FACH

Berkovits, Alejandro; Departamento de Hematología, Clinica Alemana, Santiago de Chile

Diocares, Gonzalo; Interno de Medicina, Universidad Mayor, Santiago de Chile

López, Adriana; HOSPITAL CLINICO DE LA FUERZA AEREA DE CHILE

Full text
http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3914
Abstract
ISOLATED FACTOR X DEFICIENCY IN CHRONIC MYELOMONOCYTIC LEUKEMIA. REPORT OF ONE CASE Bleeding disorders are commonly associated with hemato-oncologic diseases. We report a 68 years old male with a chronic myelomonocytic leukemia derived from a long lasting mielodysplastic syndrome that did not respond to treatment with Azacitidine. The patient was hospitalized due to tonic clonic seizures. A CAT scan showed a hematoma in the frontal lobe. A new assessment of hemostasis revealed an isolated deficiency of factor X. We speculate that this deficit could be secondary to consumption due to the chronic Myelomonocytic Leukemia.
 
Bleeding disorders are commonly associated with hemato-oncologic diseases. We report a 68 years old male with a chronic myelomonocytic leukemia derived from a long lasting mielodysplastic syndrome that did not respond to treatment with Azacitidine. The patient was hospitalized due to tonic clonic seizures. A CAT scan showed a hematoma in the frontal lobe. A new assessment of hemostasis revealed an isolated deficiency of factor X. We speculate that this deficit could be secondary to consumption due to the chronic Myelomonocytic Leukemia.
 
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