Rememorando la contribución de Goldstein y Brown al estudio del metabolismo del colesterol: A un cuarto de siglo del Premio Nobel de Medicina

Author
Cortés, Víctor; Departamentos de Diabetes, Nutrición y Metabolismo Escuela de Medicina, Pontificia Universidad Católica

Vásquez, Tatiana; Departamentos de Diabetes, Nutrición y Metabolismo Escuela de Medicina, Pontificia Universidad Católica

Arteaga, Antonio; Departamentos de Diabetes, Nutrición y Metabolismo Escuela de Medicina, Pontificia Universidad Católica

Nervi, Flavio; Departamentos de Gastroenterología Escuela de Medicina, Pontificia Universidad Católica, Santiago

Rigotti, Attilio; Departamentos de Gastroenterología Escuela de Medicina, Pontificia Universidad Católica, Santiago

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http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/1932
Abstract
THE CONTRIBUTION OF GOLDSTEIN AND BROWN TO THE STUDY OF CHOLESTEROL METABOLISM   In December 1985, the Nobel Prize of Medicine was awarded to Drs. Joseph L. Goldstein and Michael S. Brown for their fundamental scientific work on the regulation of cholesterol metabolism mediated by the low density lipoprotein receptor pathway. This article briefly reviews the academic and research accomplishments of Drs. Brown and Goldstein as a tribute to these physician-scientists for their well-deserved award and enormous contribution to biomedical science worldwide. 
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