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dc.creatorNAJIMI,MOHAMED
dc.creatorBENNIS,MOHAMED
dc.creatorMOYSES,EMMANUEL
dc.creatorCHIGR,FATIHA
dc.date2001-01-01
dc.date.accessioned2019-11-14T12:52:33Z
dc.date.available2019-11-14T12:52:33Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000100013
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/115462
dc.descriptionThe distribution of delta sleep-inducing peptide immunoreactive cell bodies, fibers, and terminal-like structures was investigated in the normal human hypothalamus during the first postnatal year, using immunohistofluorescence and peroxidase anti-peroxidase techniques. Immunolabeled perikarya were relatively few and were mostly scattered through the anterior (preoptic) and mediobasal regions (infundibular nucleus) of the hypothalamus. DSIP-immunoreactive fibers and terminal-like fibers were observed throughout the entire rostro-caudal extent of the hypothalamus. They exhibit high densities in the preoptic region, the organum vasculosum of lamina terminalis, infundibular nucleus and median eminence. Moderate to low densities of DSIP-immunoreactive fibers were observed in the other hypothalamic structures, located in the anterior and mediobasal regions of hypothalamus, such as periventricular, paraventricular, suprachiasmatic, ventromedial, dorsomedial and parafornical nuclei. In the present study, the analysis of the immunohistochemical pattern of DSIP-immunoreactive neuronal elements in the human infant hypothalamus during the first postnatal year provided evidence of the presence of several differences. We have found qualitative age-related changes in the density of DSIP immunoreactivity in several hypothalamic structures such as the anterior region and the median eminence
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dc.languageen
dc.publisherSociedad de Biología de Chile
dc.relation10.4067/S0716-97602001000100013
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceBiological Research v.34 n.1 2001
dc.subjectDSIP
dc.subjectimmunohistochemistry
dc.subjectdevelopment
dc.subjectpost-mortem
dc.subjecthuman brain
dc.titleDistribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study


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