Leadership is an essential element for promoting innovation. The literature has primarily focused on the effect of “constructive” leadership on innovation, although numerous studies point out that destructive leadership affects organizational performance. However, such literature pays little attention to the relationship between destructive leadership and innovation. This study uses an online survey of 210 employees from 80 Portuguese firms in different sectors, to test the effect of destructive leadership on behavioural innovation and how a caring climate influences such relationship. The analysis uses multiple linear regressions to test the hypotheses. Findings reveal that destructive leadership has a negative effect on innovation and on caring climate. The results show that a caring climate influences innovation in a positive way that mitigates the relationship between destructive leadership and innovation.