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dc.creatorAkkol, Esra Küpeli
dc.creatorIlhan, Mert
dc.creatorSüntar, Ipek
dc.creatorIpek, Ayten
dc.date2018-12-02
dc.date.accessioned2020-08-04T16:41:50Z
dc.date.available2020-08-04T16:41:50Z
dc.identifierhttp://www.revistas.usach.cl/ojs/index.php/blacpma/article/view/3518
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/147987
dc.descriptionSpecies of Polygala genus have been used for the treatment of inflamation and pain in Turkish traditional medicine. The aim of the present study is to assess the anti-inflammatory and analgesic activities of P. anatolica. n-Hexane, ethyl acetate and methanol extracts of the aerial parts and roots of P. anatolica were investigated for their anti-inflammatory and analgesic effects. The methanol extracts prepared from the aerial parts and roots of P. anatolica were found to be active in carrageenan- and PGE2-induced paw edema models and in Whittle method. Methanolic extract of the aerial part inhibited serotonin-induced hind paw edema, while the root extract did not exert inhibitory effect in the same model. In addition, Fr. B and C obtained from the methanol extract of P. anatolica aerial parts showed significant anti- inflammatory activity. Morover, the analgesic effect of the methanol extracts prepared from the roots and aerial parts and Fr.B and Fr.C were found to be statistically significant without inducing ulceration. The methanol extract obtained from the aerial parts of the plant and its saponoside and flavonoid fractions showed anti-inflammatory and analgesic activities in the trials.es-ES
dc.formatapplication/pdf
dc.languagespa
dc.publisherUniversidad de Santiago de Chilees-ES
dc.relationhttp://www.revistas.usach.cl/ojs/index.php/blacpma/article/view/3518/26002833
dc.sourceBoletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas; Vol. 17 Núm. 6 (2018): Vol 17, No 6: BLACPMA, Noviembre 2018; 555 - 565es-ES
dc.source0717-7917
dc.titlePolygala anatolica Boiss. et Heldr.: Is A Potential Remedy for Inflammation and Pain?es-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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