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Effect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects

dc.creatorSalazar,Martín
dc.creatorMalpeli,Agustina
dc.creatorHebert,Elvira
dc.creatorCravero,Ricardo
dc.creatorEspeche,Walter
dc.creatorSisnieguez,Cecilia Leiva
dc.creatorStavile,Rodolfo N.
dc.creatorMarch,Carlos
dc.creatorSisnieguez,Carlos Leiva
dc.creatorTavella,Marina
dc.creatorDisalvo,Liliana
dc.creatorFasano,Victoria
dc.creatorMagrini,Graciano
dc.creatorVisentin,Dimas
dc.creatorTaranto,M. Pía
dc.creatorGonzález,Horacio F.
dc.date2019-12-01
dc.date.accessioned2020-08-05T02:57:41Z
dc.date.available2020-08-05T02:57:41Z
dc.identifierhttps://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000600701
dc.identifier.urihttps://revistaschilenas.uchile.cl/handle/2250/150676
dc.descriptionABSTRACT Hypertension is one of the main risk factors for cardiovascular disease. Functional foods containing bioactive peptides have been proposed as a strategy to decrease blood pressure (BP) in subjects under no pharmacological treatment. The aim of this study was to compare the effect of low-sodium, low-fat (LSLF) cheese and LSLF cheese containing Lactobacillus delbrueckii subsp. lactis CRL 581 (LSLF581) on BP in pre-hypertensive and stage 1 hypertensive subjects. Sixty-one pre-hypertensive and stage 1 hypertensive subjects assigned to one of twos (LSLF, n= 29 and LSLF581, n= 32) participated in this 12-month prospective, randomized, double-blind, crossover trial. Twenty-four h ambulatory BP monitoring was performed at the beginning and at the end of each four-week study period. Systolic and diastolic BP decreased in both study groups, but differences between groups were not significant (systolic, −1.78 and −0.2 mmHg; diastolic, −1.54 and −0.42 mmHg in LSLF581 and LSLF, respectively). Although our results could not support a BP lowering effect of LSLF581, small BP reductions could favorably prevent cardiovascular disease development.
dc.formattext/html
dc.languageen
dc.publisherSociedad Chilena de Nutrición, Bromatología y Toxicología
dc.relation10.4067/S0717-75182019000600701
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista chilena de nutrición v.46 n.6 2019
dc.subjectBiopeptides
dc.subjectCheese
dc.subjectFunctional foods
dc.subjectLactobacillus delbrueckii
dc.subjectPre-hypertension
dc.titleEffect of cheese containing Lactobacillus delbrueckii subsp. Lactis CRL 581 on blood pressure in prehypertensive and stage 1 hypertensive subjects


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